Overview  Alzheimers disease (AD), the most common form of dementia, accounts for 64% of   every(prenominal) told dementias in Canada. The features of Alzheimers disease include a gradual   blow and continuing decline of memory, as well as changes in judgment or reasoning, and the inability to perform familiar tasks. AD is named after Alois Alzheimer, a German physician who in 1906   set off changes in the  header tissue of a 51   home old woman who had died of unusual mental illness.  Etiology and Pathophysiology.         The   aspect at etiology is unknown. Similar to other forms of part of aging. AD is a disease that  put downs brain  cellular telephones, which is not  shape part of aging. The cognitive decline in AD is a change from a previous higher level of function, impairs  overall function, and is not associated  postingh  drop of alertness and delirium         There   atomic number 18 four changes in the brain that  pretend  enjoin in Alzheimers disease:      1. Neuritic pl   aques - dense deposits or clumps of  sticking protein fragments called  gritty beta form between the  ticker cells (not  deep down the cell).   Amyloid beta is neurotoxic (poisonous to nerve cells) and leads to cell death. Deposits of amyloid beta plaques   be also found in and  close to blood vessels in the brain.      2.

   Neurofibrillary tangles - these  be intracellular (inside the cell) collections of  twist protein filaments called tau that destroy the cell from within by causing the  analyse of the neurons  maneuver/communication system with other cells.      3. Reduced levels of acetylcholine -  at that place    is a loss of specialized nerve cells deep in!    the forebrain that produce acetylcholine, a neurotransmitter essential to memory. There are elevated levels of two enzymes responsible for degrading and destroying available acetylcholine,  to wit acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). In addition, two other neurotransmitters, serotonin and norepinephrine, both of which are related to behavioral and cognitive changes, are also   passementerie back in patients with AD....If you want to get a  plentiful essay,  gear up it on our website: 
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